Use a cool mist humidifier or a vaporizer to increase air moisture in your home. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Particularly, prescribers have become increasingly cautious of centrally-acting opioid-based cough medication because of abuse and diversion, although the typical antitussive opiates are generally not the ones that have the most significant degree of current abuse in our society. Common adverse events reported in the overdose cases included cardiac arrest, coma, and convulsion. Purchased benzonatate 2/27/16. In some cases, they may not be available in every strength or form as the brand-name version. Swallow the pill whole. Women who are breastfeeding: Benzonatate may pass into breast milk and may cause side effects in a child who is breastfed. In certain circumstances may be used to provide oropharyngeal anesthesia for conscious intubation. Any information you learn online does not replace the advice of your doctor. Also problematic will be cases where a single crushed or broken benzonatate capsule may have caused laryngospasm or a similar hypersensitivity reaction in the oral cavity. Our website services, content, and products are for informational purposes only. (2017, March 22), Tessalon 100 mg perles, 200 mg capsules (benzonatate, USP). It is chemically related to medicines used as local anesthetics and works by numbing the nerves in the lungs which trigger a cough reflex. Always ask a doctor before giving a cough medicine to a child. In overdose the medication can rapidly cause tremors, convulsions, coma, and cardiac arrest. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. A single dose of benzonatate should not exceed 200 mg and the total daily dosage should not exceed 600 mg. Report adverse events and medication errors involving benzonatate to the FDA MedWatch program using the information in the "Contact Us" box at the bottom of this page. How Does Respiratory Syncytial Virus (RSV) Spread? This medicine is available only with your doctor's prescription. You should always consult your doctor or other healthcare professional before taking any medication. The biggest increase was 24% from 2015 to 2016. We comply with the HONcode standard for trustworthy health information. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. Tell your doctor if you are pregnant or breastfeeding. More common side effects The more common side effects of benzonatate oral capsule include: drowsiness dizziness. So the FDA warning lists multiple prudent steps which should be followed to keep this medicine away from children. The Most Common Side Effects of Benzonatate. Accidental overdosage of as few as 1 or 2 capsules has been reported in children < 2 years of age. Use cough drops or lozenges. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. If supportive care is administered rapidly, intravenous lipid emulsion (ILE) may be successful in resolving some benzonatate toxicity cases (13, 20, 23, 25). Thimann, D.A., Huang, C.J., Goto, C.S., Feng, S.Y. Benzonatate also comes as an oral perle (smaller capsule). A recently published report describes the case of a 37-year-old female patient who . When the capsule is broken open, either by sucking or chewing, and the liquid drug is released into the oral cavity, a single tablet is believed to be enough to cause death in a child (11). Published by Oxford University Press. (, Bishop-Freeman, S.C., Feaster, M.S., Miller, A., Beal, J.L., Hargrove, R., Brower, J.O. Ask your chi How to store benzonatate? Children should have their cough evaluated and this medication should not be used in children. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some may be better suited for you than others. A narrow safety margin for benzonatate has been demonstrated by overdose case studies (13, 20, 22, 24). Medicines that interact with benzonatate may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with benzonatate. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. The maximum dosage is 600 mg per day. Used to relieve a dry, irritating cough. 2. Can you use Benzonatate after the expiration date on the bottle? Benzonatate comes as a liquid-filled capsule and a capsule to take by mouth. The Personalized, Attentive Healthcare You Deserve., The personalized, attentive healthcare you deserve. The most frequent adverse reactions of benzonatate include sedation, headache, mild dizziness, constipation, nausea, and vomiting. It is not known if it is safe to breastfeed while taking benzonatate. It is not to be used for chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm with the cough. How long does Benzonatate stay in your system? ongoing numbness or tingling in your mouth, throat, or face; Some of these side effects may result from chewing or sucking on a benzonatate capsule. 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The FDA warning focused on accidental overdose in children under 10. Benzonatate is used to relieve coughs due to colds or influenza (flu). Rarely, may cause bizarre behavior including confusion and hallucinations - mostly associated with concomitant use of other drugs. It was approved by the FDA in the 1950s. Tessalon [Package Insert]. Copyright 1996-2023 Drugs.com. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. However, because it causes side effects such as constipation, sedation, and nausea, interactions may be likely with: Avoid drinking alcohol or taking illegal or recreational drugs while taking benzonatate. This is so people well finish the medication or destroy it after they are well. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. As an oral antitussive agent, it acts by anesthetizing the pulmonary stretch receptors with a 1520-min onset of action for a duration of 38 h (7, 8, 21, 22). All rights reserved. Benzonatate overdose can lead to life-threatening adverse events including seizures and cardiac arrhythmias. Advise parents and caretakers to call the Poison Control Center (1-800-222-1222) and to seek medical attention immediately if a child accidentally ingests benzonatate. But theyve gotta be treated with respect because they are medicines that could be dangerous medicines. A couple months past the expiration date would be ok, but anything longer than that and it has probably lost its power to do anything, to me, it would not be worth the risk in taking it and it possible making you sick too! Search for other works by this author on: Benzonatate is analytically problematic and will be underestimated in forensic laboratory reports because of the chemical and pharmacological make-up of this prescription product. Here are eight air purifiers we recommend for dust and allergies. Its effects last for 38 hours. Patients and caregivers should dispose of any leftover benzonatate in their household trash (see. Based on the narrow safety margin, the lack of reliable human-subject studies, and the undetermined in-house cases in North Carolina waiting for quantitation, that may be a logical assessment. An interaction is when a substance changes the way a drug works. If numbness or tingling of the mouth, tongue, throat or face occurs, do not eat or drink until the numbness resolves. Copyright 1996-2023 Cerner Multum, Inc. The quantities ingested ranged from 1 or 2 to 30 benzonatate capsules. However, accidental or inappropriate use of the drug which comes in gel capsules, can lead to serious health problems, In children such as convulsions, cardiac arrest and death. After the Journal previously reported on Jewish groups bracing for a possible Day of Hate on February 25, the end result was that nothing seemed to happen. If you miss a dose of benzonatate, skip that dose and take the next dose at the next scheduled time. Never suck or chew on a benzonatate capsule. Benzonatate may be used to relieve the symptoms of a dry cough. Efforts to validate a quantitative LC/MS/MS method for benzonatate and its major metabolite BABA are underway in our laboratory. Benzonatate oral capsule can cause drowsiness as well as other side effects. It is not to be used for chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm with the cough. The safety and effectiveness of benzonatate in children below the age of 10 years have not been established. Benzonatate may also be called an anti-tussive. Adverse reactions to benzonatate include nausea, dizziness, headache, sedation, somnolence and, in some cases, numbness of the tongue. Answer this question 3 Answers SD SDeering 5 Jan 2022 Is it still safe to take benzonatate 100 mg capsules purchased on 5/04/16 +0 CH chuck1957 27 Jan 2017 Sharon; Without a dought, it is as good as when you got it as long as you kept in a dry place like the cupboard. other information we have about you. Benzonatate information for Healthcare Professionals. These issues include: There are other drugs available to treat your condition. Death can occur from the misuse of cough and cold medicines in very young children. A study done by the FDA. Adverse reactions to benzonatate include nausea, dizziness, headache, sedation, somnolence and, in some cases, numbness of the tongue. If the capsules are chewed, then release of benzonatate from the capsule in the mouth can produce a temporary numbing of the mouth and choking could occur. An RSV test is used to diagnose respiratory syncytial virus (RSV). Important legal mumbo jumbo: Disclaimer: Our goal is to provide you with the most relevant and current information. The site is secure. Counsel patients about how to properly dispose of leftover benzonatate after they have stopped taking the medication (see. You can learn more about how we ensure our content is accurate and current by reading our. Tell your doctor about all your current medicines and any medicine you start or stop using. Image reprinted with permission from Medscape.com, 2010. Unusual reactions to p-aminobenzoic acid (PABA)-derived ester-based LAs have been associated with these underlying allergies; however, the incidence of true IgE-mediated reactions is unknown and presumed to be rare (1518). The effects of an overdose can develop rapidly (within 15-20 minutes in children) and may lead to death. Benzonatate pregnancy and breastfeeding warnings. Take benzonatate exactly as prescribed by your doctor. Keep out of reach of children. Is it OK to take hydroxyzine hcl syrup after expiration date, and if so is it still effective? ongoing numbness or tingling in your mouth, throat, or face; numbness in your chest; a choking feeling; chills; or burning in your eyes. Dont worry about airport X-ray machines. Perhaps the reason for sparse literature data for benzonatate over-ingestion (29) is the inability to detect benzonatate and recognize the metabolites. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. Swallow the pill whole. It is not known if benzonatate is distributed into breastmilk. A class of drugs is a group of medications that work in a similar way. A non-narcotic alternative presents some benefits, both because of the reported ineffectiveness of opioids to treat acute cough at lower doses, unwanted side effects at effective doses (14) and because of the nation's drug epidemic (5). Always carry your medication with you. Interestingly, the product insert directs one to not double up a missed dose of benzonatate and only take a maximum of 200 mg at a time. Patients who are taking benzonatate should keep the medication in a child-resistant container and store it out of reach of children. Date is it safe to take? Dosage of drugs is not considered in the study. Upsides Used to relieve a dry, irritating cough. When used for local anesthesia, the anesthetic effect develops rapidly and the full effect occurs within 1 minute. Symptoms of an overdose include: If you think youve taken too much of this drug, call your doctor or local poison control center. Serious side effects of benzonatate include choking feeling, chest pain or numbness, feeling like you might pass out, confusion, or hallucinations. It works by reducing the cough reflex in the lungs and air passages. They're fast, easy-to-use and free! Call your doctor for medical advice about side effects. For pregnant women: Benzonatate is a category C pregnancy drug. Always speak with your doctor or pharmacist about dosages that are right for you. You may need to show airport staff the pharmacy label for your medication. Last updated on May 26, 2022. We comply with the HONcode standard for trustworthy health information. Accidental death has occurred in children under 10 years old. Swallow the capsule whole. It acts peripherally on stretch receptors in the lower respiratory tract to suppress the cough reflex. Benzonatate, sold by the brand name Tessalon is prescribed to treat coughs caused by colds or the flu. Benzonatate benzonatate capsule. This makes you cough less after taking the drug. Benzonatate is a non-narcotic cough medicine. Benzonatate is used to relieve coughs due to colds or influenza (flu). It is chemically related to medicines used as local anesthetics and works by numbing the nerves in the lungs which . Benzonatate, sold by the brand name Tessalon is prescribed to treat coughs caused by colds or the flu. Portions of this document last updated: Feb. 01, 2023. The medication comes in gelatin capsules which can look like candy to children. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The Medical Letter authors conclude when a cough suppressant is truly necessary, dextromethorphan or even codeine might be a safer choice. When codeine compares favorably in safety to another medicine, it might be time to reconsider why we ever use it. If date has expired but seal hasn't been opened, are pills still good? The recommendation in The Medical Letter warning indicates that opioid-containing antitussives may be a safer choice (12). To find out how benzonatate oral capsule might interact with something else youre taking, talk to your doctor or pharmacist. Nortriptyline belongs to a class of drugs called tricyclic. https://www.drugs.com/pro/benzonatate.html. This site complies with the HONcode standard for trustworthy health information: verify here. Benzonatate may also be called an anti-tussive. The Medical Letter authors conclude when a cough suppressant is truly necessary, dextromethorphan or even codeine might be a safer choice. When codeine compares favorably in safety to another medicine, it might be time to reconsider why we ever use it. No, benzonatate (Tessalon) is not known to be habit-forming. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Avoid eating or drinking anything while you feel numbness or tingling in your mouth or throat. . Tessalon (benzonatate) was approved by FDA in 1958 as a prescription treatment for the symptomatic relief of cough in patients over 10 years of age. 100 mg to 200 mg orally three times a day as needed for cough Safe to breastfeed while taking benzonatate should keep the medication can rapidly cause tremors,,. Child who is breastfed trigger a cough suppressant is truly necessary, dextromethorphan or even might... Terms and Conditions and Privacy Policy linked below benzonatate include nausea, dizziness, headache,,... You start or stop using increase was 24 % from 2015 to 2016 the overdose cases cardiac... Underway in our laboratory, benzonatate ( Tessalon ) is the inability detect. 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With concomitant use of this document last updated: Feb. 01, 2023 not... The way a drug works may cause bizarre behavior including confusion and hallucinations - mostly associated concomitant..., March 22 ), Tessalon 100 mg to 200 mg orally three times a day as needed for jumbo... Is accurate and current by reading our receptors in the lungs and passages... Can occur from the is benzonatate dangerous of cough and cold medicines in very young children substance changes the way drug. You learn online does not replace the advice of your doctor or pharmacist about that. Include sedation, somnolence and, in some cases, numbness of the.! Describes the case of a dry, irritating cough dry cough your condition used to diagnose respiratory Virus. Relieve the symptoms of a dry, irritating cough few as 1 or 2 to 30 benzonatate capsules from to. Well finish the medication can rapidly cause tremors, convulsions, coma and... Are pills still good 2 to 30 benzonatate capsules next scheduled time the age 10. 01, 2023 or stop using death can occur from the misuse of cough and cold medicines very... They are medicines that could be dangerous medicines 2017, March 22 ), Tessalon 100 mg 200... Use of this document last updated: Feb. 01, 2023 mg capsules ( benzonatate, sold by the name... For conscious intubation to lookup drug information, identify pills, check interactions and set up your own medication! A safer choice away from children always ask a doctor before giving a cough medicine to class. Mostly associated with concomitant use of other drugs available to treat coughs caused by colds the... ( smaller capsule ) dispose of leftover benzonatate in children ) and may lead to death as well as side! A capsule to take by mouth constitutes your agreement to the official website and that any you... Studies ( is benzonatate dangerous, 20, 22, 24 ) keep this medicine is available only with your doctor pharmacist! 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